Ibuprofen Versus Ketorolac by Mouth in the Treatment of Acute Pain From Osteoarticular Trauma
Status:
Recruiting
Trial end date:
2021-10-31
Target enrollment:
Participant gender:
Summary
Pain is the leading cause of access to the paediatric emergency department (ED) and present
in up to 78% of cases.
Acute osteoarticular traumatic pain is often treated inadequately, and there is little data
about the best treatment for children. The ibuprofen and ketorolac are respectively the most
used and one of the most powerful NSAIDs. In literature, there is no direct comparison
between those two medications.
The objective of the study depends on the level of pain:
- in severe traumatic acute pain (>=7 points): to evaluate if ketorolac is superior to
ibuprofen in the treatment of pain (n=130 children, 65 allocated to ketorolac and 65 to
ibuprofen)
- in moderate traumatic acute pain (<7 points): to evaluate if ibuprofen is not inferior
to ketorolac in the treatment of pain (n=120 children, 60 allocated to ketorolac and 60
to ibuprofen)