Ibuprofen Versus Ketorolac for Pain Relief During Hysterosalpingogram

• Status: Not yet recruiting
• Trial end date: 2023-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

Hysterosalpingogram (HSG) testing is a vital part of the workup for infertility patients. It is often noted to be biggest pain that patients undergo during the workup. Several studies have attempted to find a therapy that reduces pain, with non-steroidal anti-inflammatory drugs such as oral ibuprofen the current mainstay. Our study attempts to determine which of the following NSAIDS is best at reducing pain associated with the HSG procedure: oral ibuprofen versus oral ketorolac .

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Madigan Army Medical Center
• Treatments: Ibuprofen; Ketorolac

Criteria

Inclusion Criteria:

• English speaking

• premenopausal females age 18-45

• patients currently undergoing HSG as part of routine work-up for infertility or subfertility, - - patients with negative urine pregnancy test within 24 hours of the scheduled procedure

• patients having performance of HCG between menstrual cycle days 5-12n

Exclusion Criteria:

• Non-English speaking

• patients with history of previous HSG performed

• patients with contrast allergy or other contraindications to HSG

• patients with contraindications to NSAID use

• Patients with the following:

• unwilling to consent

• positive urine pregnancy test within 24 hours of the scheduled procedure

• active renal or hepatic disease

• chronic narcotic users

• use of pain medications within 12 hours of the scheduled procedure

• patients with chronic pain conditions (fibromyalgia, complex regional pain syndrome, etc.)

• patients with unknown uterine anatomical pathology