Ibuprofen and Renal Function in Premature Infants

• Status: Completed
• Trial end date: 2006-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Purpose of the study:

1. To evaluate renal function maturation within the first month of life in very premature infants.

2. To determine whether a treatment with Ibuprofen for patent ductus arteriosus would alter renal function maturation at short term and up to 28 days of life.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Maternite Regionale Universitaire
• Collaborators: Central Hospital, Nancy, France; Ministere de la Sante et de la Protection Sociale, France
• Treatments: Ibuprofen

Criteria

Inclusion Criteria:

• Gestational Age = 27 to 31 weeks

• Postnatal age < 48 hours

• Parental Consent Obtained

Exclusion Criteria:

• Renal malformation

• Urinary tract infection

• Renal Failure

• Pulmonary Hypertension at echocardiography