Ibuprofen as a Pain Management in Pediatric Dentistry

• Status: Completed
• Trial end date: 2019-05-30
• Target enrollment: 0
• Participant gender: All

Summary

Abstract Introduction: Administration of non-steroidal anti-inflammatory drugs (NSAIDs) before tooth extraction may reduce post-surgical pain, but there is a lack of research.

Aims: To compare pain and anxiety in pediatric tooth extraction patients receiving a preoperative NSAID vs. placebo.

Design: Randomized, double-blind, placebo-controlled clinical trial. Setting: Princess Nourah Bint Abdulrahman University's (PNU's) dental clinic in Riyadh, Saudi Arabia.

Materials and Methods: Eligible pediatric tooth extraction patients were randomized to Group A, which received NSAID preoperatively, or Group B, which received placebo.

Interventions: A research coordinator (RC) measured participants prior to extraction, and 3- and 24-hours post-extraction.

Main Outcome Methods: The Wong-Baker FACES scale (WBFS) and the Modified Child Dental Anxiety Scale - Faces (MCDASf).

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Princess Nourah Bint Abdulrahman University
• Treatments: Ibuprofen

Criteria

Inclusion Criteria:

1. child must be undergoing a simple extraction under local anesthesia of one or more symptomatic primary molars including teeth with pathology such as abscess, cyst, and internal resorption

2. parent must provide consent and the child provide assent

3. must not have any systematic disease

4. must not be taking any medication that interacts with ibuprofen (the NSAID used in this study)

5. must be cooperative

• Excluded Criteria Children were excluded for

1-known allergy 2-having ever had an allergic reaction to ibuprofen 3- taking antibiotics or other medications 4-special needs due to a physical or mental disability 5-been given an analgesic prior to appointment by the guardian; 6-being treated for an emergency medical condition (e.g., cellulitis).