Identification of Sentinel Lymph Nodes With Methylene Blue and Isotope
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The aim of this study is to evaluate the performance of a double labelling method using
isotope and methylene blue dye injection to localize precisely Sentinel Lymph Node (SLN) in a
series of 100 patients with infiltrative breast cancer justifying SLN excision. Method and
patients: SLN excision will be performed on 100 patients treated for infiltrative breast
cancer. After preoperative methylene blue dye injection and lymphoscintigraphy, individual
localization of the radioactive and stained nodes will be performed. After the surgery, SLN
will be submitted to serial analysis and immunohistochemistry. A comparison of the two
methods and an economical evaluation of the complete procedure will be performed.