Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication

• Status: Completed
• Trial end date: 2010-01-01
• Target enrollment: 0
• Participant gender: Male

Summary

Duloxetine has recently been shown to be effective in reducing the pain in chronic pain patients. Duloxetine is known to exert a central mechanism, however the precise human brain structures responsible for mediating its pain-relieving properties are not known. We will use functional magnetic resonance imaging (FMRI) to investigate the neural and functional correlates of pain.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Stanford University
• Treatments: Duloxetine Hydrochloride

Criteria

Inclusion Criteria:- Males aged 18-60

• Back Pain

• Must be able to comply with study visit schedule and other study requirements

• Capable of performing the experimental tasks Exclusion Criteria:- Contraindications for MRI examination (e.g., metallic implants such as pacemakers, surgical aneurysm clips, or known metal fragments embedded in the body)

• Known hypersensitivity to duloxetine or any of the inactive ingredients

• Uncontrolled narrow-angle glaucoma