Imaging of Brain Amyloid Plaques in the Aging Population

• Status: Enrolling by invitation
• Trial end date: 2023-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective, open label, non-therapeutic, diagnostic imaging study. The purpose of this study is to utilize Pittsburgh Compound B positron emission imaging (PiB PET) to ascertain the relationship between change in amyloid burden over time, and concurrent change in clinical status.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mayo Clinic
• Collaborator: National Institute on Aging (NIA)
• Treatments: Corticosterone

Criteria

Inclusion Criteria:

• Age 30-100

• Subjects who have completed or are scheduled to undergo the neurological evaluation procedures in the Mayo Clinic Study of Aging, Mayo ADRC, or Mayo neurodegenerative disease clinics.

Exclusion Criteria:

• Subjects unable to lie down without moving for 10 minutes

• Women who are pregnant or cannot stop breast feeding for 24 hours

• Claustrophobic patients unable to tolerate the scans

• Standard safety exclusionary criteria for MRI such as metallic foreign bodies, pacemaker, etc.