Immediate Versus Delayed Treatment of Odontogenic Infections

• Status: Withdrawn
• Trial end date: 2020-10-02
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to compare the physiologic resolution of dental infections between immediate tooth extraction (control group) and administration of systemic antibiotics and delayed extraction (study groups 1 and 2). A secondary objective is two compare two different antibiotic regimens in the delayed extraction groups (study group 1 and 2).

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Boston Children's Hospital; Boston Children’s Hospital
• Treatments: Amoxicillin; Anti-Bacterial Agents; Antibiotics, Antitubercular

Criteria

Inclusion Criteria:

• Patients who present to the dental clinic or Boston Children's Hospital emergency room

• Odontogenic origin associated with a primary tooth and limited to the buccal vestibule only

• Ages of 2-11 years old

• Primary Caregiver present

• English speaking

• American Society of Anesthesiologists (ASA) classification of I

• None or current systemic antibiotic therapy regimen < 24 hours

• Able to take medication orally

• Those patients who choose to participate in the study

Exclusion Criteria:

• Infection that has spread beyond the buccal vestibule, or not detectable

• Infection is associated with a permanent adult tooth

• Ages of <2 years old or >11 years old

• American Society of Anesthesiologists classification of II or greater or poor general health.

• Renal impairment

• Immunosuppressive disease

• Recent antibiotic therapy in the last 1 to 30 days

• Allergy to penicillin

• Unable to take oral medications

• Decline participation