Immunization With BCG Vaccine to Prevent Tuberculosis Infection
Status:
Not yet recruiting
Trial end date:
2024-05-14
Target enrollment:
Participant gender:
Summary
The purpose of this research is to find out if a single dose of pre-travel vaccination with
BCG can lessen tuberculosis (TB) infection by producing an immune response when given to
adults traveling to countries with a high burden of TB. BCG will be compared with a placebo
(an inactive vaccine). BCG (Japan) is used globally but is not approved for use in the United
States, therefore it is considered experimental. Participants choosing to take part in this
research study, will be randomly assigned (this is like a coin flip) to BCG or placebo. 2000
eligible volunteers will be enrolled.
Phase:
Phase 3
Details
Lead Sponsor:
Henry M. Jackson Foundation for the Advancement of Military Medicine
Collaborators:
Uniformed Services University of the Health Sciences United States Department of Defense