Immunohistology in USDD and Correlation Between Bacterial Flora and Phlogosis
Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Diverticulosis of the colon is a frequent condition in adults in western countries and a
significant number of patients experience clinical symptoms even when the diverticulosis is
not complicated by diverticulitis.
Both central and mucosal immunity are altered in Uncomplicated Symptomatic Diverticular
Disease (USDD) and Rifaximin ameliorate clinical symptoms and normalize the immunological
abnormalities.
The Study Protocol is verify the modifications in the immunological pattern induced by
reducing bacteria related activation of immunity by Rifaximin treatment.