Impact of Adjuvant Chemotherapy in Patients With Colon Cancer

• Status: Completed
• Trial end date: 2019-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The present study aims to investigate the impact of adjuvant chemotherapy with 5-FU isolated and associated with oxaliplatin in cardiac autonomic control and endothelium-dependent vascular function in patients undergoing colectomy for stages II and III colon cancer. Will be performed evaluation of cardiac and vascular function, autonomic control, functional capacity and blood evaluations.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Sao Paulo General Hospital
• Collaborator: Fundação de Amparo à Pesquisa do Estado de São Paulo
• Treatments: Fluorouracil; Oxaliplatin

Criteria

Inclusion Criteria:

• Scale of Performance Status 0 - 1

• Patients submitted to colectomy for adenocarcinoma of colon stages II and III.

Exclusion Criteria:

• Severe pulmonary disease

• Decompensated cardiovascular disease

• Neurological disease

• Insulin-dependent diabetes mellitus

• Dialysis renal insufficiency