Impact of Antibiotic Treatment on Prostate-Specific Antigen (PSA) Variability
Status:
Terminated
Trial end date:
2011-06-01
Target enrollment:
Participant gender:
Summary
Ciprofloxacin hydrochloride has been approved by the Food and Drug Administration (FDA) for
the treatment of mild to moderate infections, including prostate infections. It has been
suggested that antibiotic treatment influences PSA levels due to the fact that an increase in
PSA levels may be caused by inflammation or swelling of the prostate. Antibiotics are used to
treat such inflammatory conditions. However, it has not been proven that antibiotics can be
used to lower PSA. This research is being done to see if treatment with the antibiotic
Ciprofloxacin hydrochloride affects the Prostate-Specific Antigen (PSA) blood test. This
study may also help doctors in deciding which patients need a prostate biopsy.