Impact of Dexamethasone on the Duration of Sensory and Motor Block Following Spinal Anesthesia

• Status: Completed
• Trial end date: 2017-10-26
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess the effect of a single-dose of intravenous dexamethasone 8 mg on the duration of sensory and motor blockade following spinal anesthesia with isobaric bupivacaine.

The hypothesis of the study is that intravenous dexamethasone will significantly prolong (by more than 20 minutes) the duration of spinal anesthesia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
• Treatments: Anesthetics; BB 1101; Bupivacaine; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate

Criteria

Inclusion Criteria:

• Patients undergoing lower body surgery under spinal anesthesia

• American Society of Anesthesiologists' physical status of 1 to 3

Exclusion Criteria:

• Contraindication to spinal anesthesia (coagulopathy, local infection at the site of injection)

• Pre-existing neuropathy or nerve block that could compromise study assessments

• Preoperative use of systemic corticosteroids

• Allergy or hypersensitivity to local anesthetics, dexamethasone or other drugs used in this study

• Patient refusal or inability to consent