Impact of Hemodialysis on Plasma Carnitine Levels in Patients With End Stage Renal Disease

• Status: Recruiting
• Trial end date: 2023-07-10
• Target enrollment: 0
• Participant gender: All

Summary

OBJECTIVES

• To assess the levels of plasma carnitine in controls and hemodialysis patients.

• To give supplementary L-carnitine to study subjects for a duration of 5months.

• To compare the values of plasma carnitine before and after L carnitine supplementation.

• To assess the role of carnitine supplementation on biochemical and clinical parameters.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bahria University
• Collaborators: Jinnah Postgraduate Medical Centre; Pakistan Navy Station Shifa Hospital; University of Karachi

Criteria

Inclusion Criteria: • Individuals of either sex (male and female).

• The study included people between the ages of 18 and 50 who had had dialysis for more than two years without taking additional antioxidants.

Exclusion Criteria:

• • Individuals with any other chronic ailment, such as cancer or tuberculosis.

• Patients with acute renal failure who are receiving hemodialysis.

• All subjects who refused to take part in the investigation.