Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion
Status:
Withdrawn
Trial end date:
2020-07-24
Target enrollment:
Participant gender:
Summary
Neural injury is a well-known complication following extreme lateral lumbar interbody fusion
(XLIF). It has been found that up to 9.4% of patients will have either temporary or
persistent neurologic deficit. This occurs with traversal of the psoas muscle or direct
injury to lumbosacral plexus or sympathetic ganglion. While often temporary, it can cause hip
flexor weakness, thigh numbness, or pain.
Several studies have demonstrated reduced patient reported pain scores following steroid
administration, particularly in the early postoperative period. However, few studies have
investigated the efficacy of intraoperative local injection of corticosteroid in reducing the
incidence and duration of postoperative pain or neurologic injury for XLIF patients.