Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy
Status:
Completed
Trial end date:
2008-01-01
Target enrollment:
Participant gender:
Summary
Oral contraceptives are known to improve menstrual cycles and symptoms in PCOS, however may
increase cholesterol. Metformin, a drug to improve insulin resistance, may benefit metabolic
state. This study is to determine whether metformin added to oral contraceptive therapy in
adolescent women with PCOS improves metabolic state.The study will also test a lifestyle
improvement program to reduce weight.