Impact of Misoprostol on Blood Loss In Myomectomy Operations

• Status: Completed
• Trial end date: 2014-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this research work is to assess the effect of using single preoperative dose of rectal misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• Premenopausal patients aged between 35 to 50 years old.

• Five or less symptomatic uterine myomas .

• Maximum diameter of the largest myoma is 6 cm .

• All myomas are subserous or intramural.

• Uterine size less than 24 weeks pregnancy

Exclusion Criteria:

• History of previous surgery.

• Allergy to Misoprostol.

• Hypertension.

• Cardiac and Pulmonary diseases.

• Patients who have bleeding disorders.

• Anemia (Hb < 10g %).

• Chronic endocrine or metabolic diseases such as Diabetes.

• Obesity (body mass index > 30 kg/m2).

• Cases that will require intraoperative conversion of myomectomy to hysterectomy.