Impact of Multiple Electrolytes Injection Ⅱ and Saline on Hyperchloremia in Patients With Aneurysmal Subarachnoid Hemorrhage:a Pilot Study

• Status: Completed
• Trial end date: 2023-05-31
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this pilot randomized trial is to compare the effect of Multiple Electrolytes Injection Ⅱand saline on the occurrence of hyperchloremia within 72h of randomization in patients with aneurysmal subarachnoid hemorrhage(aSAH). A secondary aim was to provide data for the design and power of a large-scale, multicenter, randomized controlled trial.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Capital Medical University

Criteria

Inclusion Criteria:

• Patients with aneurysmal subarachnoid hemorrhage;

• Expected ICU stay > 24 hours.

Exclusion Criteria:

• Under 18 years of age;

• Pregnancy;

• Patients at imminent risk for death within 24 hours;

• Patients with a known history of serious cardiovascular, respiratory, kidney, liver, blood, or immune disease;

• Azotemia (BUN > 200μmol/L), hypokalemia (blood potassium < 2.5mmol/L), hypocalcemia (blood calcium < 1.8mmol/L);

• Patients routinely receiving renal replacement therapy (RRT);

• Declined to participate in the study.