Impact of Periodontal Therapy on Patients With Diabetes
Status:
Completed
Trial end date:
2021-01-28
Target enrollment:
Participant gender:
Summary
With poorly controlled diabetes, periodontal status often worsens, and with severe
periodontal conditions there is often poorer glycemic control. There are few published
reports investigating the efficacy of periodontal therapy in diabetics and fewer that include
evaluation of the oral microbial profiles (the microbiome). The investigators will examine
systemic changes in diabetes status and microbiome influences on clinical response to
periodontal therapy in a randomized clinical trial of participants with and without diabetes
and with periodontal disease. Two different treatments will be used:
1. Scaling and root planning (SRP) alone, or
2. SRP and supportive periodontal therapy (SPT), the use of chlorhexidine gluconate rinse
(Paroex®) and a rubber interdental bristle cleaner (Soft-Picks) The main goal of this
clinical trial is to evaluate the effects of SRP alone versus SRP+SPT on clinical,
microbiological and immunological status in participants. A clearer understanding of how
periodontal therapy affects diabetes status could lead to the development of new
therapies for periodontal disease and diabetes.