Impact of Prophylactic Antibiotics on Bloodstream Infections After Liberation From Extracorporeal Membrane Oxygenation

• Status: Not yet recruiting
• Trial end date: 2023-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this prospective interventional study is to evaluate the impact of antibiotic prophylaxis on bloodstream infections after liberation of extracorporeal membrane oxygenation therapy. The main questions aims to answer are:

• does application of vancomycine prior to ECMO liberation have an impact of bloodstream infections?

Participants will get 1 dose of vancomycine I.V. (15-20 mg per kgKG) prior to liberation of ECMO.

Researchers will compare this interventional group to a group without antibiotic prophylaxis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universität des Saarlandes
• Treatments: Vancomycin

Criteria

Inclusion Criteria:

• adult patients older than 18 years

• ECMO-Therapy

Exclusion Criteria:

• patients younger than 18 years

• fever >38,5°C

• pregnancy

• antibiotic treatment with Vancomycine, Linezolid, Daptomycin or Tygacil on the day of liberation

• prior adverse events after application of Vancomycine