Impact of Vitamin D Repletion in Hemodialysis Patients

• Status: Completed
• Trial end date: 2013-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Dialysis patients often suffer from defects in their immune system (that part of the body which fights infection). Evidence suggests that Vitamin D deficiency may have a negative effect on immunity, and many dialysis patients are deficient in Vitamin D. We believe that by giving Vitamin D to dialysis patients who are deficient, we may help improve their immune system. This study will test that idea.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mehrotra, Anita, M.D.
• Collaborators: American Heart Association; National Kidney Foundation
• Treatments: Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

1. Age > 18 years

2. Chronic hemodialysis treatments for at least 2 consecutive months

3. 25OH-Vitamin D level < 25 ng/mL (inclusion criteria for randomization)

Exclusion Criteria:

1. History of acute renal failure requiring dialysis with potential for renal recovery

2. History of HIV/AIDS

3. Inability to provide informed consent