Impact of Vitamin D Supplementation on Lactation Associated Bone Loss
Status:
Completed
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
Studies have shown that lactation is associated with a loss of bone density from four to
seven percent at the spine and hip among women who lactate for six months. Decline in bone
density with lactation occurs rapidly. Although bone density increases after weaning, there
is controversy on whether or not it is completely restored. Epidemiological studies find no
significant negative impact of lactation on bone mass or fractures, and in fact there is
evidence that lactation has a positive effect on bone mass. We think that interventions that
attenuate this physiologic loss of bone that is associated with lactation and accelerate
restoration of bone mass after weaning may result in improved long term bone mass and
diminished fracture risk.
Phase:
N/A
Details
Lead Sponsor:
Leigh Eck, MD
Collaborator:
Bio-Tech Pharmacal, Inc.
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins