Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
Status:
Recruiting
Trial end date:
2024-07-01
Target enrollment:
Participant gender:
Summary
A two arm pilot study investigating the rate of pathologic complete response in patients with
vitamin D deficiency and triple negative breast cancer undergoing standard neoadjuvant
chemotherapy + vitamin D supplementation, including an observational arm to describe response
in patients who are not deficient. Investigators hypothesize that vitamin D supplementation
during neoadjuvant chemotherapy in operable triple negative breast cancer patients with
vitamin D deficiency, will increase the rate of pathologic complete response chain reaction
to that of vitamin D sufficient patients based on historical controls.