Improved Estimation of GFR by Cystatin C in Preventing Contrast Induced Nephropathy by NAC or Zn
Status:
Terminated
Trial end date:
2006-03-01
Target enrollment:
Participant gender:
Summary
Background Prevention of contrast media (CM) induced nephropathy (CIN) by pharmacological
prophylaxis (e.g. N-acetylcysteine; NAC) is controversially discussed. So far, in all
interventional studies assessment of kidney function was based on measurements of serum
creatinine although this surrogate biomarker has several limitations. We investigated the
antioxidants NAC and zinc (Zn) for the prevention of CIN by monitoring concomitantly serum
levels of creatinine and cystatin C.
Phase:
N/A
Details
Lead Sponsor:
Robert Bosch Gesellschaft für Medizinische Forschung mbH