Improvement of Live Babies Rates After ICSI, Using cpFT

• Status: Not yet recruiting
• Trial end date: 2024-08-26
• Target enrollment: 0
• Participant gender: Female

Summary

Demonstrate the improvement of the live births rate after ICSI by supplementing the pre-ICSI incubation medium of oocytes and that of preimplantation embryos with cpFT at the 1st embryo transfer for women under 37 years old.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Criteria

Inclusion Criteria:

• Couples eligible for a first attempt at Assisted Reproduction (AMP).

• Couples asking for Assisted Reproductive Technology, and requiring an ICS procedure.

• Women aged 18 to 36 inclusive.

• Men aged 18 to 58 inclusive

• Use of CSCM-C culture medium from Biocare / Irvine, exclusively.

• People affiliated to a Social Security scheme

Exclusion Criteria:

• Lack of consent

• Early menopause.

• Couples under IVF or Intra Uterine Insemination treatment.

• Patients resumed after a first attempt by the couple.

• People unable to follow protocol visits in France.

• Couple with a contraindication to treatment with ART.

• Women with a contraindication to treatment with ART or an associated pathology such as: hypertension, risk of eclampsia, viral risk, family genetic problems, diabetes, uterine partitions, synechiae adhesions, adenomyosis or any other contraindication judged as such by the investigator.

• AMP with donation of gametes or embryos.

• Frozen sperm.

• Participant under guardianship or guardianship