Improving Tissue Repair After Injury in the Muscle-tendon Interface Muscle Tissue Injury

• Status: Not yet recruiting
• Trial end date: 2025-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The study is a 2-week human study where 40 patients who are scheduled to undergo reconstructive knee surgery are randomized to administration of GH or placebo following or without neuromuscular electrical stimulation of hamstring muscles.The overall aim is to determine, the role of muscle connective tissue protein synthesis in muscle injury and repair.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Bispebjerg Hospital
• Treatments: Hormones

Criteria

Inclusion Criteria:

• Healthy men and women scheduled to undergo reconstructive knee surgery

• BMI 18-35

Exclusion Criteria:

• Former or current use of growth hormone or anabolic steroids

• Use of corticosteroids in the past 3 months

• Use of any medication known to affect muscle or tendon turnover

• Former participation in a study using deuterated water

• Chronic diseases