In Vitro Maturation of Human Eggs

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Because a large proportion of the embryo's quality is dependent upon the egg, this investigation focuses on treatment of the oocyte during in vitro maturation (IVM). In typical IVF cycles, the egg is recovered when it is mature and ready to be fertilized. However, at this point the oocyte's quality has been set, and cannot be altered. Therefore, to have an impact on oocyte quality the use of in IVM is critical. Development of a successful IVM protocol for clinical use would not only provide an option for women of advanced maternal age, it would also reduce the cost of IVF due to fewer exogenous gonadotropins used for stimulation, and significantly lessen the risk of ovarian hyper-stimulation.

The objective of this research study is to evaluate a newly developed oocyte maturation media system for human clinical use in assisted reproductive technology (ART).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Foundation for Fertility Research
• Collaborator: Fertility Laboratories Of Colorado
• Treatments: Follicle Stimulating Hormone; Hormones

Criteria

Inclusion Criteria:

• Infertile women who desire to conceive and come to CCRM for infertility treatment using IVF will be candidates for this study.

• Women with PCOS

• Patients can be of any race, culture, sexual orientation or ethnicity.

Exclusion Criteria:

• Minors are excluded from participation in this study.

• Women with a BMI greater than 40

• Women whose health is such that becoming pregnant carries risk significantly greater than healthy women are excluded from this study, unless they use a gestational carrier under the direction of their physician.