Incidence of Acute Laryngeal Injury Following Endotracheal Intubation
Status:
Recruiting
Trial end date:
2023-12-30
Target enrollment:
Participant gender:
Summary
The purpose of this investigation is to delineate the incidence of acute and chronic
laryngeal injury following intubation within our health system. In addition, this study seeks
to identify risk factors for airway injury that may provide information to help reduce the
incidence of injury or increase the speed of diagnosis through hospital based process
measures.
Study Aims
1. Determine the incidence of acute laryngeal injury in patients with prolonged intubation.
2. Determine the incidence of chronic laryngeal injury in the subset of patients with acute
laryngeal injury
3. Initiate a randomized control trial to investigate the ability of azithromycin and
budesonide to improve objective and subjective breathing measures in patients with Acute
Laryngeal injury (ALgI) following endotracheal intubation.