Increased Sensitivity to Pain Caused by Opioids in People Who Have Abused Prescription Opioids
Status:
Terminated
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
Managing pain in patients who abuse prescription opioids presents many challenges, including
the development of opioid-induced hyperalgesia (OIH). Hyperalgesia is a condition in which
something that usually feels slightly painful is perceived as something very painful. The
proposed study will test the efficacy of the well-known neurological medication pregabalin to
diminish OIH and chronic pain in persons who are in Suboxone (buprenorphine) or methadone
treatment for prescription drug abuse.