Incretin Effect and Use After Clinical Islet Transplantation
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
We aim to study if the administration of medications to increase the secretion of hormones
from the intestines can improve glycemic control, reduce insulin use and promote β-cell
regeneration/expansion in subjects with type 1 diabetes following islet transplantation who
are back using small doses of insulin because of early graft dysfunction. We believe that the
results will enable us to understand whether these drugs could be useful in islet transplant
recipients, particularly if glycemic control deteriorates.