Overview

Incretin Effect on the Immunological Phenotype

Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
0
Participant gender:
All
Summary
Assessment of the effect of incretin based therapies (Liraglutide and Saxagliptin) on immune cells in healthy subjects and patients with type 1 diabetes
Phase:
Phase 2
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Medical University of Graz
Treatments:
Incretins
Liraglutide
Saxagliptin
Criteria
Inclusion Criteria:

-healthy subjects or patients with type 1 diabetes

Exclusion Criteria:

- pregnancy

- treatment with GLP-1-Analoga (Liraglutide, Exenatide)

- treatment with DPP4-inhibitor (Sitagliptin, Vildagliptin, Saxagliptin)

- chronic disease including a long-term medication over 4 weeks per year (except type 1
diabetes)