Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS
Status:
Recruiting
Trial end date:
2023-06-07
Target enrollment:
Participant gender:
Summary
The investigators aim to conduct a double blind randomized clinical trial to study the
independent and additive effects of micronutrients (Resveratrol, Acetyl-L Carnitine, L
Arginine and COQ10 ) with Metformin in patients with PCOS .Women diagnosed with PCOS
according to National Institute of Health( NIH) 2012 extension of European Society of Human
Reproduction and Embryology /American Society of Reproductive Medicine ESHRE /ASRM 2003
criteria will be included according to a specific phenotype including Hyperandrogenism,
Ovulatory dysfunction and Polycystic Ovarian Morphology. The investigators propose that by
using combination therapy with micro supplements like Resveratrol, Acetyl-L Carnitine, L
Arginine and COQ10 will produce greater improvement better than or at least comparable to
Metformin in metabolic and endocrine profile of patients with PCOS.