Overview

Individual Differences in the Response to Drugs

Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to examine whether individual differences in acute responses to drugs co-vary across three drugs from different drug classes: alcohol, amphetamine and delta-9-tetrahydrocannabinol (THC). The investigators hypothesize that individuals who experience greater rewarding effects from one drug will also experience more rewarding effects from the other drugs.
Phase:
N/A
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Chicago
Treatments:
Amphetamine
Dextroamphetamine
Dronabinol
Ethanol
Criteria
Inclusion Criteria:

- English fluency

- High school education

- BMI between 19 and 26

- Individuals who report drinking at least 4 alcoholic drinks on one occasion in the
past month

Exclusion Criteria:

- individuals with a medical condition contraindicating study participation, as
determined by our physician

- individuals regularly using any contraindicated medications

- individuals with current dependence on any drug or past dependence on alcohol,
marijuana or stimulants

- individuals with a past year DSM-IV Axis I mood, anxiety, eating, or psychotic
disorder

- women who are pregnant, nursing, or planning to become pregnant in the next 3 months

- individuals who drink more than 10 alcoholic drinks per week

- individuals who currently use i) any illicit drug weekly or more frequently, ii)
stimulant prescription drugs, iii) more than 10 cigarettes per week, and iv) more than
3 cups of coffee per day