The purpose of this research study is to compare the effectiveness of commonly used
decolonization treatments (application of mupirocin antibiotic ointment to the nose and
bleach baths) when performed by individuals with a history of skin and soft tissue infection
(SSTI) in the prior year (individualized approach) in comparison to decolonization of all
household members (household approach) in an attempt to prevent Staphylococcus aureus skin
infections. The investigators hypothesize an individualized decolonization approach will be
equally as effective as a household approach to prevent SSTI.