Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 Trials
Status:
Recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare selective cyclooxygenase-2 (COX-2) and non selective
COX inhibitors with respect to the extent to which disease activity is improved without self
reported, unacceptable side effects among individual patients with axial spondyloarthritis
(AxSpA),to compare selective COX-2 and nonselective COX inhibitors impact on Health related
Quality of Life (HrQOL) and how this relates to changes in disease activity and to conduct
proteomic assessment of predictive biomarkers of non steroidal anti-inflammatory drug(NSAID)
response
Phase:
Phase 2
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston
Collaborator:
National Center for Advancing Translational Science (NCATS)