Inducing Graft Tolerance in HLA Haplotype Matched Related and 3 Ag Matched Unrelated Living Donor Kidney Transplantation
Status:
Recruiting
Trial end date:
2024-02-14
Target enrollment:
Participant gender:
Summary
This research study is to determine if donor blood stem cells given after living, related,
HLA antigen (Ag) haplotype match or living, unrelated donor kidney transplantation. Minimal
HLA antigen matching will include matching of 2 HLA antigens that can be either HLA A, B, and
/or DR. This research will change the immune system such that immunosuppressive drugs can be
completely withdrawn or reduced to minimal dose without kidney rejection.
Phase:
Early Phase 1
Details
Lead Sponsor:
Samuel Strober
Collaborators:
California Institute for Regenerative Medicine California Institute for Regenerative Medicine (CIRM)