Induction Chemotherapy With ACF Followed by Chemoradiation Therapy for Adv. Head & Neck Cancer
Status:
Completed
Trial end date:
2019-10-31
Target enrollment:
Participant gender:
Summary
This phase II trial studies the safety and effectiveness of an induction chemotherapy (ACF)
consisting of paclitaxel albumin-stabilized nanoparticle formulation (nab-paclitaxel),
cisplatin and fluorouracil followed by chemoradiation therapy in treating patients with stage
III-IV squamous cell cancer of the head and neck. ACF may be an effective way to reduce or
downgrade locally aggressive tumors, and improve the chance of eradication by chemoradiation.