Induction FOLFIRINOX Followed by Chemoradiation in Locally Advanced Pancreatic Cancer
Status:
Active, not recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
There is no a clear consensus regarding the optimal treatment strategy of locally advanced
pancreatic cancer. There is a potential role for neoadjuvant therapy to treat micrometastatic
disease with chemotherapy, as well as for the treatment of local disease with radiotherapy.
The investigators evaluated the safety and efficacy of induction FOLFIRINOX followed by a
high weekly dose of gemcitabine concurrent to radiation therapy in patients with borderline
resectable and unresectable locally advanced pancreatic cancer (LAPC).