Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer
Status:
Completed
Trial end date:
2020-02-04
Target enrollment:
Participant gender:
Summary
This trial compares induction treatment with FOLFOX with or without aflibercept in a high
risk population selected by MRI, prior to receiving standard chemoradiation (capecitabine
combined with 50.4 Gy in 28 days) and surgery, in order to evaluate the efficacy in terms of
pathologic complete response (pCR).
Phase:
Phase 2
Details
Lead Sponsor:
Grupo Espanol Multidisciplinario del Cancer Digestivo