Overview Induction of Gut Permeability by an Oral Vaccine Status: Recruiting Trial end date: 2021-12-31 Target enrollment: Participant gender: Summary This study evaluates the effect of an oral typhoid vaccine on disruption of the intestinal barrier and response of the immune system. Intestinal and whole-body responses will be measured in all participants before and after the vaccine. Phase: Early Phase 1 Details Lead Sponsor: USDA, Western Human Nutrition Research CenterTreatments: AspirinVaccines