Induction of Labor in Pregnant Women With Prelabor Rupture of Membranes - Oxytocin or Misoprostol

• Status: Active, not recruiting
• Trial end date: 2022-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of study is to compare the efficacy and safety of oral misoprostol versus oxytocin in induction of labor in pregnant women with prelabor rupture of membranes at term.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams Maternity Hospital
• Treatments: Misoprostol; Oxytocin

Criteria

Inclusion Criteria:

• Gestational age (36-42 weeks).

• Prelabor rupture of membranes within the last 24hours

• Vertex presentation

Exclusion Criteria:

1. History of medical diseases (HTN, diabetes milletus, systemic lupus erythematosus, cardiac, etc.).

2. Antepartum hemorrhage

3. Chorioamnionitis / prelabor rupture of membranes >24hours

4. Multiple pregnancy.

5. Abnormal fetal heart rate pattern upon admission

6. Intrauterine growth restriction

7. Fetal malpresentation.

8. Previous uterine scar.

9. Estimated fetal weight more than 4kg.

10. Patients already in labor

11. Contraindication for prostaglandin/oxytocin use (allergy,..)