Infant TB Infection Prevention Study

• Status: Completed
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Randomized controlled trial (RCT) of isoniazid (INH) vs. no INH to prevent Mycobacterium tuberculosis infection in HIV-exposed uninfected (HEU) infants.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Washington
• Collaborator: Thrasher Research Fund
• Treatments: Isoniazid

Criteria

Inclusion Criteria:

• HIV exposed infants

• Aged 6 weeks within (+ 4 weeks)

• Born to HIV-infected mothers

• Not premature and over 2.5 kg

Exclusion Criteria:

• Infants with known exposure to active TB in household

• Premature and < 2.5 kg