Overview

Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis

Status:
Recruiting
Trial end date:
2024-05-14
Target enrollment:
Participant gender:
Summary
This phase II trial studies how well infliximab and intravenous immunoglobulin therapy work in treating patients with pneumonitis that does not respond to steroid treatment. Immunotherapy with monoclonal antibodies such as, infliximab, may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Intravenous immunoglobulin therapy may improve pneumonitis. It is not yet known whether giving infliximab and intravenous immunoglobulin therapy will work better in treating patients with pneumonitis.
Phase:
Phase 2
Details
Lead Sponsor:
ECOG-ACRIN Cancer Research Group
Collaborator:
National Cancer Institute (NCI)
Treatments:
Antibodies
Cortisone
gamma-Globulins
Immunoglobulin G
Immunoglobulins
Immunoglobulins, Intravenous
Infliximab
Prednisone
Rho(D) Immune Globulin