Influence of Corticoids on Renal Function in Cardiac Surgery

• Status: Unknown status
• Trial end date: 2015-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Hypothesis: Corticoid treatment in cardiac surgery works renal protective.

Study design: Randomized, double blind trial in which one group of patients will receive methylprednisolone and the other group (control) will receive placebo NaCl 0.9%.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Ghent
• Treatments: Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• age between 20-80 year

• patients scheduled for elective cardiac surgery.

• preoperative creatinine levels of < 2mg/dl

• no corticoid treatment

Exclusion Criteria:

• non-elective surgery

• patiënts with renal dysfunction: creatinine > 2mg/dl

• patiënts treated with corticoids