Influence of Depth of Anesthesia on Pupillary Reactivity to a Standardized Stimulus

• Status: Completed
• Trial end date: 2016-03-01
• Target enrollment: 0
• Participant gender: All

Summary

A standardized tetanic stimulation is applied to patients under propofol-remifentanil TCI, in a cross-over fashion, at two different levels of anesthesia monitored by the BIS: BIS 25 and BIS 55. Remifentanil target remains constant during the whole study period (1 ng/ml). Pupillary reflex dilation is recorded after each stimulation.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hôpital Armand Trousseau
• Treatments: Anesthetics; Propofol; Remifentanil

Criteria

Inclusion Criteria:

• ASA 1-2

• scheduled for an idiopathic scoliosis surgical correction

Exclusion Criteria:

• Ophtalmologic pathology

• Neurologic or muscular pathology

• Metabolic pathology

• Chronic pain