Influence of Gender on Interaction of Propofol and Dexmedetomidine

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effect of gender on pharmacodynamic interaction of propofol and dexmedetomidine, exploring the effect of gender on propofol unconsciousness median effective concentration with different dose dexmedetomidine.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Guangzhou General Hospital of Guangzhou Military Command
• Treatments: Dexmedetomidine; Propofol

Criteria

Inclusion Criteria:

1. Weight:18≦ BMI≦25

2. Written informed consent from the patient or the relatives of the participating patient.

Exclusion Criteria:

1. A previous history of intolerance to the study drug or related compounds and additives.

2. Existing significant haematological, endocrine, metabolic or gastrointestinal disease.