Influence of Intrathecal Dexamethasone Administration for Proximal Femoral Fractures

• Status: Completed
• Trial end date: 2017-07-04
• Target enrollment: 0
• Participant gender: All

Summary

Spinal anesthesia blocks acute pain in older patients with femur fracture. Delirium is a common complication seen after femur fracture, affecting approximately 10-16% of patients. It is associated with increased mortality at 1st year, delayed rehabilitation efforts, prolonged length of hospital stay, poorer functional outcomes, and increased risk of nursing home placement.

Intrathecal dexamethasone administration improves quality of anesthesia in patients with femur fracture compared to conventional spinal anesthesia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: General Hospital Sveti Duh
• Treatments: Anesthetics; BB 1101; Bupivacaine; Dexamethasone; Dexamethasone acetate; Levobupivacaine

Criteria

Inclusion Criteria:

• cooperative ASA 2 and ASA 3 status patients with proximal femoral fractures of one leg

• agreed to be enrolled in the study (Informed Consent signed)

Exclusion Criteria:

• patients refused to be enrolled in the study

• patients with pre-existing cognitive disturbances before surgery

• conditions or diseases with corticosteroid therapy, long term corticosteroid, diabetes mellitus, neurological conditions or tumors, neuroendocrine disorders or tumors

• breaking the study protocols

• patients who no longer wanted to be enrolled in the study

• unexpected events when the study already started