Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Acute Myocardial Infarction
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
The purpose of the IMPRESSION study is to determine whether intravenous administration of
morphine prior to ticagrelor administration in ST-segment elevation myocardial infarction
(STEMI) patients and in non-ST-segment elevation myocardial infarction (NSTEMI) patients
alters the plasma concentrations of ticagrelor and its active metabolite and whether it is
associated with any negative impact on the antiplatelet effect of ticagrelor.