Influence of Oxytocin on Approach-avoidance Tendencies to Social and Non-social Stimuli

• Status: Completed
• Trial end date: 2020-01-30
• Target enrollment: 0
• Participant gender: Male

Summary

In this study, a randomized, placebo-controlled between-subject design is adopted to investigate the effect of a single-dose of intranasally administered OT on approach-avoidance related motivational tendencies during the processing of a series of social and non-social, positively and negatively valenced stimuli. To obtain a behavioral measure of approach-avoidance tendencies, participants will be able to control the viewing time of the presented stimuli, by pressing 'up' or 'down' on a keyboard. During stimulus presentation neurophysiological recordings will be performed to obtain a neural measure of approach-avoidance motivational tendencies, based on electroencephalographic recordings (EEG: frontal alpha asymmetry). Also assessments of autonomic arousal, based on skin conductance recordings will be collected.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: KU Leuven
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• right-handed

• male

• age between 18 and 35

• Normal or adjusted-to-normal vision (with lenses only)

• Dutch as mother tongue

Exclusion Criteria:

• female

• age below 18 or above 35

• neurological or psychiatric condition (e.g. epilepsy, stroke, concussion), (e.g. anxiety disorder, depression)

• use of psychotropic medication (e.g. anxiolytics, antidepressants)