Influence of Profound Muscle Relaxation on Muscle Trauma and Postoperative Pulmonary Function
Status:
Unknown status
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
Although deep anesthesia can produce skeleton muscle relaxation,unnecessary deep anesthesia
often had adverse cardiac effects and was related to 2-year mortality in cancer patients.The
use of muscle relaxants allowed the depth of anesthesia to be optimized.However, for many
anesthesiologists,in fear of residual postoperative neuromuscular blockade,intraoprative
administration of muscle relaxants had to be minimized in spite of poor surgical conditions.
This study, however, is designed to test the hypothesis that profound neuromusclular blockade
reduces muscle trauma caused by self-retaining retractor and thus cut down postoperative
analgesic requirement.On the other hand,profound muscle relaxation can decrease postoperative
diaphragmatic dysfunction and abdominal muscle trauma, which can improve postoperative
pulmonary function.